ICD-10 Code for PCOS in Women’s Health Care

Polycystic ovary syndrome (PCOS) is one of the most common endocrine conditions affecting women of reproductive age. Women with PCOS often report irregular menstrual cycles, metabolic shifts, and symptoms related to androgen excess. Because PCOS can affect multiple body systems and evolve over time, accurate use of the ICD-10 code for PCOS is important for longitudinal documentation and interdisciplinary communication.

In this article, we’ll provide a clear overview of the correct ICD-10 code for PCOS, explain when it is appropriate to use this diagnosis code, outline commonly associated conditions that may also require documentation, and include a practical clinical example. The goal is to support accurate, clinically grounded documentation that reflects both the diagnosis and the patient’s presentation.

Clinical overview of PCOS in women’s healthcare

PCOS is a heterogeneous condition, meaning that symptoms and clinical impact can vary widely between individuals. Some women present primarily with menstrual irregularity, while others seek care related to fertility concerns, dermatologic symptoms, or metabolic health changes. These differences matter clinically—and they should be reflected in documentation.

Across care settings, PCOS may affect patients in several functional domains, including:

• Menstrual regularity and ovulatory function

• Fertility planning and reproductive goals

• Dermatologic symptoms that affect quality of life

• Metabolic health, including insulin resistance and weight-related concerns

Recognizing this variability helps clinicians document PCOS as a systemic endocrine condition rather than a single gynecologic finding.

What is the ICD-10 code for PCOS?

The primary ICD-10 code for PCOS is: E28.2 – Polycystic ovarian syndrome

This code falls under the ICD-10-CM category E28: Ovarian dysfunction, within the endocrine chapter.¹ Its classification reflects that PCOS is a hormonal and metabolic condition, not a structural ovarian disorder.

E28.2 should be used when a clinician has formally established the diagnosis of PCOS through clinical assessment, supported as appropriate by laboratory findings, imaging, or longitudinal history. It should not be used for isolated ovarian cysts or menstrual disorders in the absence of a confirmed PCOS diagnosis.

Clinical features that support the use of E28.2

Accurate use of the ICD-10 code for PCOS depends on clear clinical documentation supporting the diagnosis. In practice, clinicians often reference features such as:

• Irregular or absent menstrual cycles

• Clinical or laboratory evidence of hyperandrogenism

• Polycystic ovarian morphology identified on imaging

Although ICD-10-CM does not mandate specific diagnostic criteria, documenting the clinical rationale for diagnosing PCOS helps ensure that E28.2 is appropriately supported in the medical record.

It’s important to recognize that PCOS is also associated with long-term metabolic and cardiometabolic risk, making accurate documentation important for continuity of care and population health tracking.

Commonly related ICD-10 codes used with PCOS

While E28.2 represents the underlying endocrine diagnosis, women’s health encounters often involve additional symptoms or conditions that warrant separate documentation. Reporting related codes alongside E28.2—when clinically relevant—helps reflect the full scope of the encounter.

Menstrual and ovulatory disorders

Irregular cycles and amenorrhea are common reasons women with PCOS seek care. Related codes may include:

• N91.2 – Amenorrhea, unspecified

• N92.6 – Irregular menstruation, unspecified

Metabolic and endocrine codes

Many individuals with PCOS also present with metabolic concerns. Depending on clinical findings, additional codes may include:

• E66.9 – Obesity, unspecified

• R73.03 – Prediabetes

Symptom and functional codes

Some encounters focus on symptom management rather than diagnostic confirmation. Depending on presentation, relevant codes may include:

• L68.0 – Hirsutism

• R10.2 – Pelvic and perineal pain

• M54.50 – Low back pain, unspecified

• R53.83 – Other fatigue

Coding example with the ICD-10 code for PCOS

Clinical scenario

A woman with a previously confirmed diagnosis of polycystic ovary syndrome returns for a follow up visit to discuss ongoing menstrual irregularity and worsening fatigue. She reports missed cycles over the past several months and notes that low energy levels are beginning to interfere with her ability to maintain her usual work and exercise routines. Her chart includes prior laboratory findings consistent with hyperandrogenism and a pelvic ultrasound documenting polycystic ovarian morphology.

The visit focuses on reviewing symptom progression, reinforcing the existing diagnosis, and addressing functional concerns related to fatigue and cycle irregularity.

Example coding structure

• E28.2 – Polycystic ovarian syndrome

• N92.6 – Irregular menstruation, unspecified

• R53.83 – Other fatigue

In this case, E28.2 captures the established endocrine diagnosis of PCOS, while the additional codes reflect symptoms actively evaluated and documented during the encounter. Together, the codes support a clear record of both the underlying condition and its current clinical impact.

Documentation tips for women’s health encounters

High-quality documentation supports the appropriate use of the ICD-10 code for PCOS and ensures that clinical decision-making is clearly represented. Helpful documentation practices include:

• Clearly linking reported symptoms or functional concerns to the established PCOS diagnosis

• Including relevant laboratory results, imaging findings, or longitudinal history that support diagnostic reasoning

• Distinguishing PCOS from other endocrine or gynecologic conditions with overlapping presentations

When PCOS is documented during pregnancy, include relevant comorbidities (e.g., obesity, gestational diabetes) when they are present and addressed in the visit.²

Supporting women’s health care beyond the diagnosis

Documenting the ICD-10 code for PCOS establishes the diagnosis, but many women require ongoing support for symptoms and functional concerns that extend beyond a single visit. Fatigue, pelvic health symptoms, activity limitations, and metabolic considerations often evolve over time and benefit from continued monitoring and reinforcement.

Tools that support structured follow-up care can help clinicians translate documented diagnoses into ongoing, guideline-aligned management. Medbridge’s Women’s Health solution includes Pathways designed to complement in-person women’s health care by supporting patient education, conservative management, and symptom monitoring aligned with documented diagnoses such as PCOS.

In practice, Pathways may support clinicians by:

• Reinforcing patient education tied to the documented diagnosis

• Supporting conservative management of pelvic health, musculoskeletal, and activity-related concerns

• Tracking patient-reported outcomes and symptom changes over time

• Identifying when additional clinical review or in-person care may be needed

When paired with clear documentation of PCOS and related symptoms, these tools can help clinicians maintain continuity of care between visits—while ensuring the medical record reflects how care is delivered and adjusted over time.

Why accurate ICD-10 coding matters in women’s health

Polycystic ovary syndrome affects multiple aspects of women’s health, including reproductive, metabolic, and functional domains. Accurate use of E28.2 helps clearly communicate the presence of PCOS across care teams and supports consistent, longitudinal documentation. Including associated symptoms and comorbid conditions ensures that coding reflects the patient’s presentation and the clinical focus of care.

At a broader level, clear ICD-10 coding for PCOS supports continuity of care and contributes to population-level understanding of how women’s health conditions are managed over time. When diagnoses and related symptoms are documented accurately, clinicians and organizations are better positioned to track care patterns, coordinate services, and respond to evolving patient needs.

This article is provided for informational purposes only and is not intended as medical, legal, or billing advice. ICD-10-CM coding requirements may vary based on payer policies, clinical documentation, and regulatory updates. Clinicians and organizations should consult official coding guidelines and relevant regulatory resources when making coding and billing decisions.

References

1. ICD10Data.com. (2026). 2026 ICD-10-CM diagnosis code E28.2: Polycystic ovarian syndrome. https://www.icd10data.com/ICD10CM/Codes/E00-E89/E20-E35/E28-/E28.2

2. Chen X, Kong L, Piltonen TT, Gissler M, Lavebratt C. Association of polycystic ovary syndrome or anovulatory infertility with offspring psychiatric and mild neurodevelopmental disorders: a Finnish population-based cohort study. Hum Reprod. 2020 Oct 1;35(10):2336-2347. doi: 10.1093/humrep/deaa192. PMID: 32866965; PMCID: PMC7518708. https://pmc.ncbi.nlm.nih.gov/articles/PMC7518708/